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The antibodies are involved in release of complement and anaphylatoxins which can cause or exacerbate DHF/DSS. These systems are inextricable and strongly associated with dengue pathogenesis.Dengue Background and SignificanceThe Dengue Virus is a member of the family Flaviviridae along with other noted viruses Yellow Fever, West Nile, and Japanese Encephalitis. Dengue is a positive stranded RNA ar
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Ana (70112-2699) USA Email: David G Nielsen - dnielsen@tulane.eduPublished: 27 November 2009 Virology Journal 2009, 6:211 doi:10.1186/1743-422X-6-Received: 27 October 2009 Accepted: 27 NovemberThis article is available from: http://www.virologyj.com/content/6/1/211 ?2009 Nielsen; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribu
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Ana (70112-2699) USA Email: David G Nielsen - dnielsen@tulane.eduPublished: 27 November 2009 Virology Journal 2009, 6:211 doi:10.1186/1743-422X-6-Received: 27 October 2009 Accepted: 27 NovemberThis article is available from: http://www.virologyj.com/content/6/1/211 ?2009 Nielsen; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribu
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Ana (70112-2699) USA Email: David G Nielsen - dnielsen@tulane.eduPublished: 27 November 2009 Virology Journal 2009, 6:211 doi:10.1186/1743-422X-6-Received: 27 October 2009 Accepted: 27 NovemberThis article is available from: http://www.virologyj.com/content/6/1/211 ?2009 Nielsen; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribu
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Ana (70112-2699) USA Email: David G Nielsen - dnielsen@tulane.eduPublished: 27 November 2009 Virology Journal 2009, 6:211 doi:10.1186/1743-422X-6-Received: 27 October 2009 Accepted: 27 NovemberThis article is available from: http://www.virologyj.com/content/6/1/211 ?2009 Nielsen; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribu
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Ana (70112-2699) USA Email: David G Nielsen - dnielsen@tulane.eduPublished: 27 November 2009 Virology Journal 2009, 6:211 doi:10.1186/1743-422X-6-Received: 27 October 2009 Accepted: 27 NovemberThis article is available from: http://www.virologyj.com/content/6/1/211 ?2009 Nielsen; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribu
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Risk. Mild dengue fever presents with headache, fever, rash, myalgia, osteogenic pain, and lethargy. Severe disease can manifest as dengue shock syndrome (DSS) or dengue hemorrhagic fever (DHF). Symptoms of DSS/DHF are leukopenia, low blood volume and pressure encephalitis, cold and sweaty skin, gastrointestinal bleeding, and spontaneous bleeding from gums and nose. Currently, there are no therape
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Risk. Mild dengue fever presents with headache, fever, rash, myalgia, osteogenic pain, and lethargy. Severe disease can manifest as dengue shock syndrome (DSS) or dengue hemorrhagic fever (DHF). Symptoms of DSS/DHF are leukopenia, low blood volume and pressure encephalitis, cold and sweaty skin, gastrointestinal bleeding, and spontaneous bleeding from gums and nose. Currently, there are no therape